AE at least possibly related to imatinib, ocurring in more than one patient and all SAE
| AE with possible relation | SAE | |||
|---|---|---|---|---|
| Event | % | Event | No of events (no of patients) | Attribution |
| Oedema | 80 | Haematuria (hospitalisations) | 7 (1) | Not related |
| Nausea | 73 | Pneumonia | 2 (2) | Unlikely |
| Myalgias | 67 | C difficile infection | 2 (1) | Not related |
| CK elevation | 43 | Infected ulcer | 2 (2) | Unlikely |
| Fatigue | 40 | Death (pneumonia) | 1 (1) | Not related |
| Anaemia | 27 | Acute gastroenteritis | 1 (1) | Not related |
| Pyrosis | 13 | Acute myocardial infarction | 1 (1) | Not related |
| Vomiting | 13 | Anaemia blood transfusion | 1 (1) | Not related |
| Weight loss | 13 | Fall | 1 (1) | Not related |
| Headaches | 13 | Fluid overload | 1 (1) | Probably |
| Effusions | 10 | Rectal prolapse, haemorrhoidal bleed | 1 (1) | Unlikely |
| Hypocalcemia | 7 | Nephrolithiasis | 1 (1) | Not related |
| Dry skin | 7 | Partial small bowel obstruction | 1 (1) | Not related |
| Erectile dysfunction | 7 | Bleeding post renal biopsy (hospitalisation) | 1 (1) | Not related |
| Generalised weakness | 7 | Tachyarrhythmia/cardiomyopathy | 1 (1) | Possibly |
| Light-headedness | 7 | |||
AE, adverse event; CK, creatine kinase; SAE, serious adverse event.