| IFNγ*ng/ml | IFNγ, FA added | IFNγ, anti IL 10 added | IFNγ, FA and anti IL 10 | |
|---|---|---|---|---|
| T = 0 h | 53(12) | 39(10)2 | 94(17) | 78(16) |
| T = 2 h | 19(5)1 | 48(12)3 | 27(6)4 | 93(17) |
*Mean (SEM). 12h after intake of MTX, IFNγ production is inhibited (p = 0.0001); 2Folinic acid by itself inhibits IFNγ production (p < 0.0001); 3Folinic acid completely reverses the inhibition by MTX; 4In the presence of anti-IL-10 simular results were obtained.