| Celecoxib (n = 3987) | Incidence (% of patients) Diclofenac (n = 1985) | Ibuprofen (n = 1986) | |
|---|---|---|---|
| Peripheral oedema | 3.7 | 3.5 | 5.2* |
| Generalised oedema | 0.5 | 0.6 | 1.0* |
| Hypertension (HTN) | 2.0 | 2.0 | 3.1* |
| Aggravated HTN | 0.8 | 0.6 | 1.2 |
| Creatinine and/or BUN elevation** | 1.3 | 2.1* | 1.4 |