| Celecoxib (n = 8800) | NSAIDs (n = 4394) | OR, 95% CI | |
|---|---|---|---|
| UGI Tol, n (%) | |||
| Dyspepsia | 422 (4.8)* | 259 (5.9) | 1.2 (1.1–1.5) |
| Abdominal pain | 423 (4.8)* | 274 (6.2) | 1.3 (1.1–1.5) |
| Nausea | 207 (2.4)* | 151 (3.4) | 1.5 (1.2–1.8) |
| Serious GI events, n (inc/100 pt yrs) | |||
| Possible events? | 83 (4.8) | 61 (7.1) | 1.5 (1.1–2.1) |
| Ulcer complics? | 2 (0.1)* | 7 (0.8) | 7.0 (1.5–33.8) |
| Symptomatic ulcer/complics? | 18 (1.0)* | 18 (2.1) | 2.0 (1.0–3.8) |
?investigator-determined; ?confirmed;
↵* p < 0.05.