Table 1

Summary statistics for Immunochip, validation and meta-analysis of selected SNPs

rs	chr	bp	Gene	Risk/non-risk	Immunochip (cases=1962, controls=8923)			Validation (cases=1177, controls=2155)		Meta-analysis (cases=3139, controls=11 078)
rs	chr	bp	Gene	Risk/non-risk	RAF	p Value	OR	p Value	OR	p Value	OR	I2	Q
rs2476601	1	114 377 568	PTPN22	A/G	0.10	1.29E-05	1.28	1.28E-05	1.44	1.49E-09	1.32	0	0.65
rs4795067	17	26 106 675	NOS2	G/A	0.34	1.94E-07	1.21	7.42E-03	1.25	5.27E-09	1.22	0	0.75
rs984971	2	163 224 521	KCNH7	G/A	0.36	3.62E-06	0.84	0.02	0.87	2.29E-07	0.85	0	0.61
rs1306395	2	61 076 272	LINC01185	C/T	0.43	2.99E-05	0.86	0.04	0.88	3.43E-06	0.87	0	0.85
rs7552167	1	24 518 643	IFNLR1	A/G	0.14	1.53E-05	0.79	0.10	0.88	7.36E-06	0.82	35.6	0.20
rs8106664	19	10 728 030	SLC44A2	G/T	0.23	3.28E-06	0.81	0.13	0.89	1.67E-06	0.83	0	0.52
rs2392581	7	38 573 234	AMPH	G/A	0.42	6.90E-05	0.87	0.17	0.93	4.42E-05	0.88	51.7	0.10
rs8103241	19	13 122 612	NFIX	G/A	0.46	9.08E-05	0.87	0.19	0.92	5.41E-05	0.88	0	0.52
rs1133071	9	32 455 674	DDX58	C/T	0.30	3.36E-05	1.17	0.20	1.09	2.49E-05	1.15	64.9	0.06
rs6713082	2	62 516 544	B3GNT2	A/C	0.24	4.59E-05	1.18	0.46	1.05	9.44E-05	1.15	71.7	0.03
rs2298428	22	21 982 892	YDJC	T/C	0.18	4.38E-05	1.20	0.56	1.04	2.35E-04	1.14	66.8	0.03
rs8016947	14	35 832 666	NFKBIA	T/G	0.44	9.65E-05	0.87	0.73	1.02	1.49E-03	0.91	70.1	0.04
rs7895120	10	129 064 193	DOCK1	T/C	0.14	5.29E-05	0.80	0.87	1.01	1.44E-03	0.87	62.9	0.04

bp, base position; chr, chromosome; I², heterogeneity index for ORs; Q, Cochrane's Q statistic for heterogeneity of ORs; RAF, risk allele frequency;