Clinical characteristics of gout patients with severe kidney disease
| Characters | All patients (n=25) | Baseline eGFR | ||
|---|---|---|---|---|
| <45 (n=13) | <30 (n=6) | <15 (n=6) | ||
| Age (years) | 66.1±12.2 | 66.5±12.8 | 68.2±11.0 | 63.2±11.6 |
| Gender, male | 20 (80%) | 11 (84.6%) | 5 (83.3%) | 4 (66.7%) |
| Duration of gout (mon) | 64.7±57.0 | 66.8±61.8 | 49.0±44.1 | 68.1±58.7 |
| Cause of CKD | ||||
| Hypertensive nephrosclerosis | 3 | 1 | 1 | 1 |
| Diabetic kidney disease | 8 | 3 | 3 | 2 |
| Chronic glomerular nephritis | 3 | 1 | 0 | 2 |
| Others | 3 | 3 | 0 | 0 |
| Not available | 8 | 5 | 2 | 1 |
| Serum uric acid (mg/dL) | 8.4±2.0 | 8.8±1.9 | 8.9±2.8 | 7.2±0.7 |
| eGFR (ml/min per 1.73m2 ) | 26.7±8.2 | 36.9±4.2 | 24.9±4.6 | 6.3±3.1 |
| Creatinine (mg/dL) | 3.7±3.5 | 1.9±0.2 | 2.0±0.5 | 9.2±3.3 |
| Dose of febuxostat (mg/day) | 44.0±20.0 | 44.6±21.8 | 53.3±20.7 | 33.3±10.3 |