Disease characteristics of RA patients according to presence of T allele in STAT4 rs7574865 SNP
| GG genotype | GT or TT genotype | P value | |
|---|---|---|---|
| (n=297) | (n=92) | ||
| Female, n (%) | 246 (82.8) | 78 (84.8) | 0.66 |
| RF positivity, n (%) | 198 (67.4) | 62 (67.4) | 0.89 |
| Anti-CCP positivity, n (%) | 113 (38) | 42 (45.7) | 0.31 |
| Extra-articular involvement | 87 (29.3) | 35 (38) | 0.33 |
| Joint surgery | 21 (7) | 10 (10.9) | 0.28 |
| Biologic DMARD requirement, n (%) | 126 (42.4) | 35 (38) | 0.46 |