Seronegative RASeropositive RAp
n=35 (14.8%)n=202 (85.2%)
DAS2,43.9 (1.1)3.4 (1.1)0.02
PD score1,314 [7–29]6 [2–12]<0.001
GS score1,336 [21–52]16 [10–24]<0.001
Tot US score1,362 [34–70]22 [14–36]<0.001
SJC118 [11–25]8 [4–13]<0.001
CRP19 [5–34]7 [3–18]0.15
ESR115 [10–30]20 [12–32]0.40
Ritchie Articular Index18 [3–16]7 [4–12.5]0.54
Physician Global252.1 (20.9)38.2 (20.0)<0.001
Patient Global252.1 (27.3)49.2 (23.7)0.53
EQ-5D10.59 [0.06–0.73]0.66 [0.23–0.72]0.22
Pain VAS147.7 (27.0)47.7 (23.5)>0.99
Fatigue VAS141.6 (30.1)40.0 (28.8)0.78
RAID score14.9 (2.4)4.4 (2.1)0.21

  • ↵1 Median [25–75 percentiles].

  • ↵2 Mean (SD).

  • ↵3 US examinations were performed by experienced sonographers using a validated gray-scale (GS) and power-Doppler (PD) semi-quantitative scoring system with ranges 0-3 in 32 joints.

  • ↵4 Original DAS-ESR based on 44-SJC and Ritchie articular index.