Parameter | Patients with very early diagnosis of SSc | Controls | p Value | ||||
---|---|---|---|---|---|---|---|
Number of patients | Mean value±SD | Median | Number of patients | Mean value±SD | Median | ||
LOS Pmax (mmHg) | 55 | 34.54±16.06 | 33 | 24 | 40.45±7.89 | 40.30 | 0.012 |
LOS Pm (mmHg) | 55 | 10.21±5.55 | 9.10 | 24 | 11.51±2.66 | 11.45 | 0.024 |
Peristalsis Speed (sec) | 41* | 31.91±14.74 | 30 | 24 | 36.85±10.45 | 36.65 | 0.005 |
Peristalsis Pmax (mmHg) | 41* | 43.47±20.09 | 38.80 | 24 | 69.14±10.11 | 69.40 | <0.001 |
Peristalsis Pm (mmHg) | 41* | 20.24±9.96 | 16.90 | 24 | 34.94±4.61 | 34.80 | <0.001 |
Peristalsis duration (sec) | 41* | 3.88±1.03 | 3.70 | 24 | 3.50±0.37 | 3.45 | 0.132 n.s. |
UOS Pmax (mmHg) | 55 | 90.86±58.10 | 76.50 | 24 | 81.91±35.48 | 75.45 | 0.881 n.s. |
UOS Pm(mmHg) | 55 | 35.79±24.45 | 28.60 | 24 | 28.78±11.22 | 25.85 | 0.519 n.s. |
*Number of patients for whom it was possible to evaluate the manometric parameter (in 14/55 patients peristalsis was absent).
LOS, lower oesophageal sphincter; n.s., not significant; Pm, mean pressure; Pmax, maximum pressure; SSc, systemic sclerosis; UOS, upper oesophageal sphincter.