Continuous predictors of sustained remission for active treatment groups
| Predictor | Quartiles of response, n/N (%) | P value* | |||
|---|---|---|---|---|---|
| ETN 25 mg+MTX | |||||
| First DAS28 remission | Days 0–57 | 58–179 | 180–273 | ≥274 | |
| 12/15 (80) | 16/20 (80) | 8/16 (50) | 4/12 (33) | 0.003 | |
| First DAS28 LDA | Days 0–29 | 30–57 | 58–183 | ≥184 | |
| 12/14 (86) | 12/20 (60) | 10/15 (67) | 6/14 (43) | 0.041 | |
| Mean DAS 28, week 52 | DAS28 ≤1.55 | >1.55–1.91 | >1.91–2.16 | >2.16 | |
| 14/16 (88) | 11/16 (69) | 7/15 (47) | 8/16 (50) | 0.014 | |
| MTX | |||||
| Age, BL | 19–39 years | 40–48 | 49–60 | ≥61 | |
| 11/15 (73) | 8/22 (37) | 2/15 (13) | 5/13 (39) | 0.024 | |
| CRP level, week 52 | 0–0.5 mg/L | >0.5–1.09 | >1.09–2.91 | >2.91 | |
| 9/16 (56) | 8/14 (57) | 6/18 (33) | 2/16 (13) | 0.005 | |
↵* Mantel-Haenszel chi-square correlation (trend) test.