Comparison of patients with reduced dose vs standard dose of TCZ
| 8 mg/kg dose (N=18) | 4–6 mg/kg optimized dose (N=15) | p | |
|---|---|---|---|
| TCZ levels | 8.64±16.6 | 2.62±2.7 | 0.064 |
| % suboptimal levels | 50% | 73% | 0.284 |
| IL6 | 4.93±3.8 | 5.64±3.2 | 0.593 |
| DAS28-ESR | 3.26±1 | 2.67±1.2 | 0.169 |
| CRP | 0.55±1.2 | 0.56±1 | 0.977 |