Overview of Observational Adverse Events (AEs)
| MTX (N=306) | ADA (N=459) | |
|---|---|---|
| Any AE | 125 (40.8) | 142 (30.9) |
| At least “possibly drug related” per the investigator | 63 (20.6) | 71 (15.5) |
| Severe AE | 12 (3.9) | 22 (4.8) |
| Serious AE | 16 (5.2) | 30 (6.5) |
| AE leading to discontinuation of study drug | 23 (7.5) | 25 (5.4) |
| Infectious AE | 64 (20.9) | 80 (17.4) |
| Serious infectious AE | 7 (2.3) | 12 (2.6) |
| Injection site-related AE | 3 (1.0) | 20 (4.4) |