| Group 1 (n=41) | Group 2 (n=14) | |||
|---|---|---|---|---|
| Baseline | After 24 week | Baseline | After 24 week | |
| Age, years | 49 (41–60) | 53 (46–57) | ||
| TC, mmol/l | 5,8 (4,8–6,3) | 6,1 (5,5–6,8)* | 6,0 (5,0–7,8) | 6,2 (5,2–7,8) |
| LDL-C, mmol/l | 3,7 (2,9–4,2) | 3,8 (3,2–4,5) | 4,0 (2,7–5,4) | 3,7 (3,2–5,4) |
| TG, mmol/l | 1,3 (0,7–1,7) | 1,4 (1,0–1,9) | 1,4 (1,1–1,8) | 1,5 (1,4–2,0) |
| HDL-C, mmol/l | 1,3 (1,1–1,6) | 1,6 (1,4–2,1)* | 1,5 (1,1–1,7) | 1,5 (1,3–1,9) |
| AI | 4,2 (3,3–5,0) | 3,6 (3,0–4,5)* | 4,4 (3,3–5,4) | 4,2 (3,2–5,8) |
| SI, ì/ñ | 20 (8,4–20) | 8,6 (6,8–10,7)* | 9,8 (7,5–20,0) | 11,3 (8,5–20) |
| RI, % | 90 (58–90) | 69 (56–76) | 66 (56–90) | 85 (70–90) |
| Stiff arteries, % | 52 | 15* | 28 | 36 |
| cIMTmax, mm | 0,93 (0,83–1,1) | 0,85 (0,74–0,97)* | 0,92 (0,83–1,0) | 0,90 (0,82–1,0) |
| SMI, % | 47 | 24* | 28 | 28 |
Data are presented in median values and interqurtile range (unless otherwise noted).
↵* p<0,05 before and after RTX treatment (nonparametric paired Wilcoxon test).