Table 1
HLA-B27+ (N=270)HLA-B27− (N=383)Univariable analysisMultivariable analysisDiagnostic utility measures
N (%)N (%)ORORSenSpePPVNPVLR+LR−
A: Individual Characteristic of IBP
 Morning stiffness >30 min171 (63.3)216 (56.4)1.34*1.1063.343.644.262.81.120.84
 Improve with exercise, not with rest91 (33.7)114 (29.8)1.2033.770.244.460.01.130.94
 Alter. buttock pain86 (31.9)110 (28.7)1.1631.971.343.959.71.110.96
 Insidious onset184 (68.1)241 (62.9)1.2668.137.143.362.31.080.86
 Awakening 2nd half night149 (55.2)163 (42.6)1.66***1.53**55.257.447.864.51.300.78
 Response to NSAIDs182 (67.4)217 (56.7)1.58***1.46**67.443.345.665.41.190.75
B: Combination of IBP characteristics
 Calin criteria98 (36.1)99 (25.8)1.63**36.374.249.762.31.410.86
 Berlin criteria173 (64.1)194 (50.7)1.74**64.149.347.166.11.260.73
 ASAS criteria85 (31.5)74 (19.3)1.92***31.580.753.562.31.630.85
 Night + NSAID response (2/2)108 (40)109 (28.5)1.68**40.071.549.862.81.400.84
 Calin + Night + NSAID response (6/7)58 (21.5)45 (11.7)2.06**21.588.356.361.51.840.89
 Berlin + NSAID response (3/5)154 (57.0)153 (39.9)2.00***57.060.150.266.51.430.72
 ASAS + NSAID response (5/6)66 (24.4)51 (13.3)2.11***24.486.756.461.91.830.87