| Outcome measure | Usual care (n=60)* | ENAT group (n=68)* | ||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Week 16 | Week 32 | F2,118 (p-value) | Baseline | Week 16 | Week 32 | F2,134 (p-value) | |
| ASES-Pain | 25.3 (11.2) | 26.5 (10.2) | 2751 (10.9) | 2.03 (0.135) | 23.4 (9.1) | 27.0 (9.8) | 30.7 (10.3) | 37.5 (<0.001) |
| ASES-Other symptoms | 34.2 (12.7) | 35.0 (13.9) | 35.3 (14.5) | 0.40 (0.673) | 30.6 (11.5) | 34.5 (12.6) | 38.7 (12.3) | 37.2 (<0.001) |
| AIMS2-Physical | 3.1 (2.6) | 3.0 (2.3) | 3.0 (2.5) | 0.09 (0.917) | 3.1 (2.0) | 2.8 (2.0) | 2.8 (2.1) | 2.35 (0.099) |
| AIMS2-Symptoms | 5.0 (3.2) | 4.6 (3.1) | 5.1 (3.3) | 2.34 (0.101) | 5.4 (2.6) | 4.7 (2.9) | 4.6 (2.7) | 11.8 (<0.001) |
| AIMS2-Affect | 3.7 (2.1) | 3.8 (1.9) | 4.1 (2.3) | 2.18 (0.117) | 4.3 (2.2) | 4.1 (2.1) | 3.6 (2.0) | 12.0 (<0.001) |
| AIMS2-Social | 5.5 (1.7) | 5.5 (1.7) | 5.7 (1.9) | 1.86 (0.160) | 5.6 (1.8) | 5.5 (1.9) | 5.7 (2.0) | 1.35 (0.263) |
| AIMS2-Work* | 2.0 (2.7) | 3.4 (3.5) | 2.4 (5.1) | 3.84 (0.028) | 2.3 (3.1) | 2.8 (3.3) | 2.8 (3.5) | 0.60 (0.552) |
| Total PKQ | 8.6 (2.4) | 8.7 (2.3) | 9.1 (2.8) | 1.96 (0.146) | 8.6 (2.3) | 9.0 (2.2) | 9.2 (2.3) | 5.22 (0.007 |
↵* Missing data imputed except for AIMS2-SF-Work for 59 patients who were working.