B cells/μl | Plasmablasts/plasma | FLCκ | FLCλ | |
---|---|---|---|---|
cells/μl | (mg/l) | (mg/l) | ||
Induction therapy | ||||
MMF (n=41) | 81.4* | 1.0****^^^^ | 17.5**^ | 22.3* |
(2.8–365.0) | (0.0–11.7) | (8.9–151.0) | (10.0–150.0) | |
CYC (n=23) | 32.5*°°° | 7.3**** | 34.9** | 30.2* |
(4.8–206.1) | (0.1–90.9) | (1.6–246.0) | (4.1–153.0) | |
Controls (n=39) | 118.2°°° | 3.8^^^^ | 26.4^ | 28.0 |
(14.7–1020.0) | (0.5–61.4) | 26.4^ | 28.0 | |
Maintenance therapy | ||||
MMF (n=53) | 98.8*** | 0.9**^^^^ | 17.1^^ | 19.3^ |
(0.8–553.4) | (0.0–11.7) | (8.9–151.0) | (10.4–150.0) | |
AZA (n=41) | 39.1***§ § § § | 2.4** | 22.0 | 22.0 |
(4.7–152.4) | (0.0–18.7) | (7.9–152.0) | (1.2–142.0) | |
MTX (n=19) | 52.2° | 1.1°° | 30.1 | 20.6 |
(16.5–317.8) | (0.2–15.1) | (8.5–89.9) | (6.8–77.0) | |
Controls (n=51) | 124.3§ § § §° | 4.4^^^^°° | 25.1^^ | 27.1^ |
(14.7–1020.0) | (0.4–61.4) | (9.2–66.8) | (11.9–127.0) |
Results are presented as median (range); statistically significant differences (Dunn's multiple comparisons test): one (p<0.05), two (p<0.01), three (p<0.001), four (p<0.0001) symbols *°^§.