Table 1. Associations between RA Parameters and Future MACEa
| Assessments, wk 24 | Age-Adjusted Hazard Ratio (95% CI) | p |
|---|---|---|
| SJC (28)b | 1.092 (1.051, 1.136) | <0.0001 |
| TJC (28) | 1.054 (1.018, 1.092) | 0.0034 |
| DAS28 | 1.351 (1.118, 1.633) | 0.0018 |
| EULAR (Good vs. No Response) | 0.295 (0.122, 0.714) | 0.0067 |
| AUC of DAS28 to wk 24, score-years | 1.714 (1.018, 2.886) | 0.0426 |
| Assessments, change from baseline to wk 24c | ||
| SJC | 1.084 (1.034, 1.136) | 0.0008 |
| TJC | 1.043 (1.001, 1.086) | 0.0439 |
| DAS28 | 1.293 (1.043, 1.602) | 0.0191 |
aHR estimated from Cox model with stated variable, age and other adjusters as noted; no imputation of missing values except last-observation-carried-forward for missing SJC or TJC at wk 24. bInterpretation of HR: After adjustment for age, one additional SJC at wk 24 was associated with a 9% increased hazard for MACE. cAlso adjusted for value of predictor; HR >1 indicates pts with less improvement were at higher risk for MACE.