Table 1. Differences between cases and controls. Univariate analysis
| All (n=670) | Controls (n=607) | Cases (n=63) | p-value | |
|---|---|---|---|---|
| Age, years (SD) | 47.1 (14.7) | 47.5 (14.7) | 43.5 (14.4) | 0.040 |
| Female, n (%) | 602 (89.9) | 542 (89.3) | 60 (95.2) | 0.137 |
| Evolution of RA/SLE, years (SD) | 7.5 (6.8) | 7.6 (6.9) | 7.5 (6.3) | 0.919 |
| SLE, n (%) | 120 (17.9) | 96 (15.8) | 24 (38.1) | <0.001 |
| Prednisone, n (%) | 470 (70.1) | 424 (69.9) | 46 (73) | 0.601 |
| Methotrexate, n(%) | 579 (86.4) | 526 (86.7) | 53 (84.1) | 0.577 |
| Azathioprine, n(%) | 81 (12.1) | 70 (11.5) | 11 (17.5) | 0.170 |
| Sulfasalazine, n(%) | 289 (43.1) | 268 (44.2) | 21 (33.3) | 0.099 |
| MMF, n (%) | 37 (5.5) | 25 (4.1) | 12 (19) | <0.001 |
| Antimalarial, n (%) | 366 (54.6) | 325 (53.5) | 41 (65.1) | 0.080 |
| Leflunomide, n (%) | 23 (3.4) | 20 (3.3) | 3 (4.8) | 0.469 |
| Cyclophosphamide, n (%) | 11 (1.6) | 8 (1.3) | 3 (4.8) | 0.076 |
| Biological therapy, n (%) | 127 (19) | 120 (19.8) | 7 (11.1) | 0.095 |
Abbreviations: SD, standard deviation.