Table 1. Outcomes (% pts) after IR to ADA+MTX (N=259) or PBO+MTX (N=348)
| Wk 26 | Wk 52 | Wk 78 | ||
|---|---|---|---|---|
| ACR70 | PBO+MTX[IR]→ADA+MTX | 7* | 32 | 39* |
| ADA+MTX[IR]→ADA+MTX | 13 | 27 | 30 | |
| DAS28<3.2 | PBO+MTX[IR]→ADA+MTX | 10* | 50* | 53* |
| ADA+MTX[IR]→ADA+MTX | 19 | 41 | 42 | |
| DAS28<2.6 | PBO+MTX[IR]→ADA+MTX | 4 | 33* | 40* |
| ADA+MTX[IR]→ADA+MTX | 8 | 23 | 27 | |
| SDAI ≤3.3 | PBO+MTX[IR]→ADA+MTX | 1 | 16 | 26* |
| ADA+MTX[IR]→ADA+MTX | 3 | 13 | 15 | |
| ΔmTSS<0.5 | PBO+MTX[IR]→ADA+MTX | 68* | 69* | 70* |
| ADA+MTX[IR]→ADA+MTX | 85 | 82 | 82 | |
| HAQ<0.5 | PBO+MTX[IR]→ADA+MTX | 19 | 35 | 36 |
| ADA+MTX[IR]→ADA+MTX | 26 | 30 | 31 |
*P<0.05 between groups.