Outcome* | DAS28CRP Response | Wk 26 | Wk 30 | Wk 36 | Wk 44 | Wk 52 | Wk 66 | Wk 78 |
---|---|---|---|---|---|---|---|---|
WPAI-AI | <3.2 | 13.3 | 12.6 | 13.5 | 12.3 | 11.7 | 11.7† | 10.2† |
≥3.2 | 21.8 | 19.6 | 26.1 | 25.7 | 34.6 | 39.6 | 40.7 | |
WIS | <3.2 | 3.0 | 2.7 | 2.3 | 2.6† | |||
≥3.2 | 5.8 | 7.2 | 7.4 | 10.9 | ||||
HAQ-DI | <3.2 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 |
≥3.2 | 0.5 | 0.5 | 0.6 | 0.8 | 0.9 | 0.9 | 1.0 | |
PASS | <3.2 | 82.6 | 78.5 | 79.8 | 78.7 | 80.3 | 83.2 | 87.6† |
≥3.2 | 60.7 | 64.3 | 53.6 | 64.3 | 60.7 | 50.0 | 42.9 |
*Mean response rates, except PASS, which is % of patients reporting a positive response. †2-tailed, significant difference in change from baseline (wk 0) between response groups, P<0.05.