Table 1. Change in haemostatic factors in all 22 RA patients
| Baseline | 2 weeks | 4 weeks | 26 weeks | |
|---|---|---|---|---|
| DAS44 | 3.9 (0.6) | – | – | 1.6 (0.9)** |
| ESR (mm/h) | 25 (12-43) | – | – | 4 (3-7)** |
| CRP (mg/L) | 13.0 (5.5-29.5) | 2.5 (2.5-2.7)** | 2.5 (2.5-4.5)** | 2.5 (2.5-2.7)** |
| aPTT (sec) | 29.9 (28.5-34.9) | 26.2 (25.1-31.4)** | 26.8 (25.5-29.9)** | 27.9 (26.6-30.4)* |
| PT (sec) | 11.2 (0.4) | 11.3 (0.5) | 11.1 (0.5) | 11.2 (0.5) |
| FVIII (%) | 142 (105-179) | 151 (112-196)* | 152 (123-193) | 127 (111-170) |
| D-dimer (FEU/L) | 1.18 (0.63-3.34) | 0.55 (0.29-1.26)** | 0.49 (0.26-0.84)** | 0.25 (0.21-0.78)** |
| F1+2 (pmol/L) | 342 (253-496) | 192 (146-305)* | 212 (160-285)** | 213 (153-319)* |
| PAI-1 (ng/ml) | 35 (25-49) | 40 (19-63) | 24 (16-53) | 42 (17-73) |
| vWF (%) | 115 (87-149) | 121 (86-157) | 138 (94-189)* | 101 (86-143) |
Values are mean (SD) or median (IQR) *p<0,05 and **p<0.001 change compared to baseline.