Table 1 Outcome week 26
| COBRA (n=81) | COBRA-light (n=81) | P | |
|---|---|---|---|
| ΔDAS44 | –2.50 (1.21) | –2.18 (1.10) | NS |
| Absolute DAS44 | 1.63 (0.96) | 1.77 (1.14) | NS |
| Minimal disease activity (DAS44<1.6) | 49% | 41% | NS |
| ΔHAQ | –0.8 (0.6) | –0.8 (0.7) | NS |
| ΔTender joints | –14 (11) | –13 (11) | NS |
| ΔSwollen joints | –11 (6) | –10 (6) | NS |
| ΔESR, mm/h | –21.5 (–37; –8) | –13.5 (–34; –4) | NS |
| ΔPatient’s global assessment disease activity, (0–100) | –34 (–59; –7) | –41 (–65; –17) | NS |
| ΔPhysician’s global assessment disease activity, (0–100) | –36 (–59; –9) | –31 (–54; –10) | NS |
| ACR 20 response | 72% | 72% | NS |
| ACR 50 response | 56% | 62% | NS |
| ACR 70 response | 37% | 49% | NS |
| EULAR good response | 75% | 65% | NS |
| EULAR non-response | 6% | 11% | NS |
| ACR/EULAR remission (Boolean) | 15% | 24% | NS |