	12 weeks		18 weeks		24 weeks		30 weeks
	mC	SLE	mC	SLE	mC	SLE	mC	SLE
Maximal Relaxation to Ach (%)	99±1	99±4	98±2	90±2^†	98±1	81±2^†^‡	93±1*	69±2^†^§
L-NAME inhibition on Ach (%)	53±2	52±3	52±3	42±1^†	54±3	30±2^†^‡	44±1*	10±1^†^§
Maximal Relaxation to SNP (%)	98±3	98±3	97±3	99±2	98±2	97±2	94±2	85±3^†^§
Potentiating effect of Ifx (%)	0±1	1±2	1±1	9±1^†	0±2	17±2^†^‡	2±2	1±1

*p<0.05 vs other groups of mC; ^†p<0.05 vs age-matched mC; ^‡p<0.01 vs 18 week-SLE; ^§p<0.01 vs 24 week-SLE.