Table 1. Changes in DAS28 and secondary outcomes between the two groups (PP results)

RLC Mean (SD)NLC Mean (SD)Mean Difference (95% CI)
DAS28 Week 13-0.11 (1.48)-0.04 (1.30)-0.17 (-0.53, 0.20)
DAS28 Week 260.03 (1.49)0.05 (1.22)-0.12 (-0.49, 0.25)
DAS28 Week 390.18 (1.61)0.36 (1.19)-0.25 (-0.62, 0.12)
DAS28 Week 520.18 (1.41)0.07 (1.22)0.01 (-0.36, 0.38)
Average (pooled) differences between the two groups over the whole follow-up period
 DAS280.07 (1.50)0.11 (1.24)-0.13 (-0.42, 0.15)
 Pain-3.06 (27.3)1.62 (26.8)-2.39 (-7.85, 3.07)
 Fatigue1.97 (27.4)-1.26 (25.4)3.95 (-1.33, 9.24)
 Stiffness5.78 (61.5)-4.90 (52.9)8.30 (-3.28, 19.9)
 RAQoL0.64 (5.86)0.07 (4.93)0.17 (-1.40, 1.75)
 HAQ0.01 (0.46)0.06 (0.48)-0.06 (-0.19, 0.08)
 HAD-Anxiety0.76 (3.46)-0.03 (2.69)0.67 (-0.12, 1.46)
 HAD-Depression0.25 (3.19)0.17 (2.89)0.03 (-0.71, 0.77)
 ASES-2.83 (15.4)-0.46 (17.0)-0.46 (-4.37, 3.44)
 EQ5D-VAS-2.05 (21.6)1.30 (18.9)-1.44 (-5.68, 2.80)