Table 1. Relative efficiencies of RA core data set measures to distinguish change over 6 months in GUEPARD tight control vs ESPOIR routine care
| Variable | Baseline | Change over 6m | P | Standardized response mean | Relative Efficiency | ||
|---|---|---|---|---|---|---|---|
| GUEPARD | ESPOIR | GUEPARD | ESPOIR | ||||
| Tender joint count (0–28) | 14.0±6.7 | 14.1±6.8 | –10.9 | –7.7 | 0.005 | 2.84 | 1.00 |
| Swollen joint count (0–28) | 10.1±4.9 | 10.7±5.7 | –8.5 | –7 | 0.06 | 1.83 | 0.41 |
| Physician global (VAS 0–100) | 67.6±17.2 | 65.9±18.1 | –50.2 | –32.7 | <0.0001 | 4.32 | 2.31 |
| Patient global (VAS 0–100) | 68.1±18.7 | 67.9±21.9 | –48.7 | –27 | <0.0001 | 5.03 | 3.13 |
| ESR (mm/h) | 37.3±22.4 | 39.5±25.7 | –20.1 | –18.8 | 0.7 | 0.34 | 0.01 |
| CRP (mg/l) | 28.7±33.4 | 29.8±32.3 | –22.2 | –17.1 | 0.33 | 0.98 | 0.12 |
| HAQ score (0–3) | 1.5±0.6 | 1.5±0.7 | –0.87 | –0.66 | 0.07 | 1.88 | 0.43 |
| Pain score (VAS 0–100) | 59.5±22 | 55.7±20.7 | –41.8 | –22.9 | <0.0001 | 4.56 | 2.57 |