Table 1. Subgroup analysis of outcomes following 10 years of ADA therapy
| RF(–) | RF(+) | ≤2 yrs | >2 yrs | |
|---|---|---|---|---|
| Completed 10 years, n/N (%) | 77/228 (34) | 209/618 (34) | 38/118 (32) | 248/727 (34) |
| ACR20, % | 78 | 79 | 81 | 78 |
| ACR50, % | 63 | 52 | 72 | 53 |
| ACR70, % | 34 | 32 | 47 | 31 |
| DAS28(CRP) ≤3.2, % | 74 | 70 | 84 | 69 |
| DAS28(CRP) <2.6, % | 64 | 55 | 68 | 56 |
| HAQ-DI <0.5, % | 45 | 41 | 61 | 40 |
| Discontinuation for adverse event, % | 25 | 22 | 19 | 24 |