Table 1. Cardiovascular parameters in the SSc patients and healthy controls

Variable	Patients	Controls	P value*
	Median [IQR]	Median [IQR]
ADMA	0.86 [0.80–0.90]	0.57 [0.52–0.59]	<0.0001
CFR	2.69 [2.54–2.98]	3.2 [3.0–3.6]	0.0033
IMT Dx	0.69 [0.66–0.79]	0.55 [0.49–0.61]	0.0006
IMT Sx	0.71 [0.69–0.75]	0.46 [0.40–0.56]	0.0006
PWV Dx	7.8 [6.7–10.8]	6.3 [6.1–6.9]	0.0390
PWV Sx	9.3 [8.0–11.1]	6.6 [5.3–6.9]	0.0039
Stiffness Index (β) Dx	10.4 [7.6–16.3]	0.95 [0.72–1.1]	0.0004
Stiffness Index (β) Sx	13.0 [11.5–17.2]	0.89 [0.72–1.3]	0.0004

IQR: interquartile range. ADMA: asymmetric dimethylarginine; CFR: coronary flow reserve; IMT: intima-media thickness; PWV: pulse wave velocity. *Mann-Whitney U test.