Table 1. Clinical efficacy parameters at baseline and at the end of treatment (median and IQR are presented)

Week 0Week 12p
DAS286.36 (5.98-6.78)4.73 (3.85-5.64)<0.0001
SJC7 (5–0)3 (1-4)<0.0001
TJC17 (13–20)14 (3–20)0.0563
General health, mm53 (44–70)38.5 (25–54)0.0001
ESR, mm/h35.5 (32–50)14.5 (10–30)<0.0001
Activity by patient, mm57 (50–65)38 (21–59)0.0198
Activity by physician, mm55 (37–60)35.5 (15–5 )<0.0001
Morning stiffness, min330 (180–1440)152.5 (60–290)0.018