Instrument | Domain | T2T-related responder week 26 | T2T-related non-responder | |||
---|---|---|---|---|---|---|
Mean change from baseline (N=66†) | Week 26 mean change from baseline (N=85) | |||||
Mean change | SD | p-value* vs non-responder | Mean change | SD | ||
HAQ | Functional disability | -0.36 | 0.54 | 0.0079 | -0.12 | 0.43 |
SF-36 | Bodily pain | 23.9 | 20.1 | <.0001 | 9.7 | 17.1 |
General Health | 8.9 | 17.2 | 0.0773 | 4.3 | 14.2 | |
Mental Health | 8.6 | 16.6 | 0.0582 | 3.0 | 14.7 | |
Physical Functioning | 14.2 | 18.5 | 0.0009 | 5.0 | 21.1 | |
Role-emotional | 21.2 | 50.5 | 0.6334 | 18.0 | 46.5 | |
Role-physical | 33.3 | 39.1 | 0.0036 | 15.3 | 39.4 | |
Social Functioning | 15.3 | 27.4 | 0.0373 | 7.6 | 24.6 | |
Vitality | 18.3 | 20.4 | 0.0003 | 8.5 | 19.5 |
†One patient missing data for General Health domain, *Wilcoxon Two sample test.