Table 1. Diagnostic value of symptoms and clinical findings for classification of HFNEF

	Sensitivity	Specificity	LR+	95% CI	LR–	95% CI
Edema	0,68	0,67	2,05	1.44–2.92	0,48	0.28–0.82
Dyspnea NYHA-class >1	0,94	0,72	3,34	2.47–4.53	0,09	0.02–0.34
Dyspnea NYHA-class >2	0,65	0,86	4,76	2.81–8.04	0,41	0.25–0.66
Dyspnea NYHA-class >3	0,06	1,00			0,94	0.84–1.02
Orthopnea	0,32	0,95	6,34	2.50–16	0,71	0.56–0.91
Nocturia >1	0,61	0,79	2,89	1.85–4.52	0,49	0.31–0.77
Nocturia >2	0,35	0,92	4,65	2.12–10	0,70	0.54–0.91
Abnormal Auscultation	0,16	0,91	1,73	0.64–4.61	0,92	0.78–1.09
S3 Gallop	0,06	0,95	1,30	0.27–5.98	1,00	0.89–1.09
NT-proBNP >222 pg/ml	1,00	0,86	7,38	4.53–11	0,00	0.00–0.28
Abnormal ECG	0,61	0,69	2,01	1.36–2.97	0,56	0.35–0.88
Abnormal Chest X-Ray	0,55	0,81	2,82	1.72–4.61	0,56	0.38–0.84
Cardio Thoracic Ratio>.55	0,52	0,81	2,78	1.66–4.65	0,59	0.41–0.86
Concentric Hypertrophy	0,45	0,79	2,20	1.30–3.73	0,69	0.49–0.96
Reduced GLS >–18	0,54	0,81	2,88	1.72–4.84	0,57	0.38–0.86
Diastolic Dysfunction 1°	0,29	0,79	1,37	0.71–2.63	0,90	0.71–1.15
Diastolic Dysfunction 2°	0,48	0,69	1,54	0.89–2.42	0,75	0.52–1.08
Diastolic Dysfunction 3°	0,13	0,98	7,61	1.46–40	0,89	0.77–1.02