Osteoarthritis–adult height comparison | Osteoarthritis–BMI comparison | |||||
---|---|---|---|---|---|---|
All data | r2 = 0.2 | r2 = 0.05 | All data | r2 = 0.2 | r2 = 0.05 | |
No of SNPs† | 489098 | 63802 | 27728 | 461707 | 55275 | 24599 |
p Value* | 0 | 2.62×10−7 | 3.04×10−5 | 0 | 6.41×10−5 | 1.24×10−5 |
Tested p value** | 3.30×10−6 | 5.33×10−6 | 1.10×10−3 | 6.19×10−11 | 2.91×10−4 | 2.25×10−4 |
No of permutations | 100000 | 100000 | 100000 | 100000 | 100000 | 100000 |
Permutation p value | 0.0128 | <1×10−5 | 0.0014 | 0.00374 | 0.04716 | 0.02288 |
†Directly typed only analysed.
*p Value of original analysis.
**p Value of the overlap for directly typed SNPs only. This is the p value that the permutation analysis is tested against.
BMI, body mass index; SNPs, single nucleotide polymorphism.