Analysis of shared excess signals between osteoarthritis and normal height variation and osteoarthritis and BMI
| Osteoarthritis–normal adult height comparison | Osteoarthritis–BMI comparison | |||
|---|---|---|---|---|
| Total no of SNPs | 62280 | 64702 | ||
| Signal definition (p value) | Overlapping SNPs (n) | p Value for overlap | Overlapping SNPs (n) | p Value for overlap |
| 0.5 | 28194 | 0.5189 | 23526 | 0.4299 |
| 0.1 | 3571 | 0.0026 | 1867 | 0.5814 |
| 0.05 | 1491 | 3.04×10−5 | 584 | 0.7483 |
| 0.04 | 1160 | 1.00×10−6 | 412 | 0.6315 |
| 0.03 | 814 | 1.00×10−6 | 267 | 0.1715 |
| 0.02 | 511 | 1.00×10−16 | 143 | 0.0368 |
| 0.01 | 213 | 6.20×10−4 | 50 | 0.0356 |
| 0.005 | 92 | 0.0173 | 20 | 0.0057 |
| 0.001 | 17 | 0.5999 | 4 | 1.2×10−5 |
| 0.0005 | 8 | 0.1278 | 3 | 4.8×10−17 |
BMI, body mass index; SNP, single nucleotide polymorphism.