Description | CpG Chr coordinate | Gene region | |
---|---|---|---|
Hypermethylated genes | |||
PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 18:60386672 | Body |
RXRA | Retinoid X receptor, α | 9:137243592 | Body |
CYFIP1 | Cytoplasmic FMR1 interacting protein 1 | 5:22985092 | Body |
ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | 5:178712051 | Body |
CD55 | CD55 molecule, decay accelerating factor for complement | 1:207497486 | Body |
CABLES1 | Cdk5 and Abl enzyme substrate 1 | 18:20717693 | Body |
HAS1 | Hyaluronan synthase 1 | 19:52223620 | Body |
ITGB8 | Integrin, β 8 | 7:20449718 | 3′UTR |
HBEGF | Heparin-binding EGF-like growth factor | 5:139722098 | Body |
PTPN14 | Protein tyrosine phosphatase, non-receptor type 14 | 1:214588993 | Body |
COL4A2 | Collagen, type IV, α 2 | 13:110979651 | Body |
COL4A1 | Collagen, type IV, α 1 | 13:110892021 | Body |
TGFBR2 | Transforming growth factor, β receptor II (70/80 kDa) | 3:30684783 | Body |
EGF | Epidermal growth factor | 4:110837358 | Body |
ITGBL1 | Integrin, β-like 1 (with EGF-like repeat domains) | 13:102109225 | Body |
TIMP2 | TIMP metallopeptidase inhibitor 2 | 17:76871734 | Body |
MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 | 5:56115499 | Body |
FOXO1 | Forkhead box O1 | 13:41223175 | Body |
Hypomethylated genes | |||
CHI3L1 | Chitinase 3-like one (cartilage glycoprotein-39) | 1:203156625 | TSS |
WISP3 | WNT1 inducible signalling pathway protein 3 | 6:112375870 | Body |
STK24 | Serine/threonine kinase 24 | 13:99201496 | Body |
MMP20 | Matrix metallopeptidase 20 | 11:102473828 | Body |
EGFLAM | EGF-like, fibronectin type III and laminin G domain | 5:38403758 | Body |
PTGIS | Prostaglandin I2 (prostacyclin) synthase | 20:48183673 | Body |
DCBLD1 | Discoidin, CUB and LCCL domain containing 1 | 6:117802710 | TSS |
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 (ASK1) | 6:136915088 | Body |
MGMT | O-6-methylguanine-DNA methyltransferase | 10:131323903 | Body |
CDK14 | Cyclin-dependent kinase 14 | 7:90794392 | 3′UTR |
STAT3 | Signal transducer and activator of transcription 3 | 17:40489721 | Body |
ADAM32 | ADAM metallopeptidase domain 32 | 8:38965386 | Body |
RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 5:80460495 | Body |
CASP1 | Caspase 1, apoptosis-related cysteine peptidase | 11:104916773 | TSS |
P2RX6 | Purinergic receptor P2X, ligand-gated ion channel, 6 | 22:21381565 | 3′UTR |
TRAF2 | Tumour necrosis factor receptor-associated factor 2 | 9:139796499 | Body |
MEFV | Mediterranean fever | 16:3307037 | TSS |
p value cut-off of <0.05 used for determining significance. If a gene had multiple significant loci then the coordinates and gene region information of the most significant locus given.