Mothers' characteristics | N=133 |
---|---|
Age (years) | 36±5 |
BMI (kg/m2) | 25±5 |
Primary APS | 108 (81%) |
Purely thrombotic APS | 37 (28%) |
SLE | 18 (14%) |
Laboratory data | |
Lupus anticoagulant | 33 (25%) |
Anticardiolipin IgG/M | 66 (50%)/16 (12%) |
Anti-β2 glycoprotein-I antibodies G/M | 32 (25%)/25 (19%) |
Double/triple positivity | 20 (15%)/10 (8%) |
Treatment before pregnancy | |
Corticosteroids | 21 (16%) |
Hydroxychloroquine | 15 (11%) |
Aspirin | 26 (19%) |
Treatment during pregnancy | |
Aspirin and low-molecular weight heparin | 118 (90%) |
Corticosteroids | 25 (19%) |
Hydroxychloroquine | 15 (11%) |
Actual pregnancy outcome | |
Gestational hypertension/diabetes mellitus | 12 (9%)/14 (11%) |
Intrauterine growth restriction | 12 (9%) |
Preeclampsy/hellp syndrome | 3 (2%) |
Thrombosis | 3 (2%) |
Values are means with SD and numbers with frequencies.
APS, primary antiphospholipid syndrome; BMI, body mass index; SLE, systemic lupus erythematosus.