Patient characteristics, BCG vaccination status and clinical risk factors by concordance or discordance group
| Concordance | Discordance | |||
|---|---|---|---|---|
| Parameter | TST+/IGRA + (n=66) | TST–/IGRA–(n=1302) | TST+/IGRA–(n=107) | TST–/IGRA + (n=54) |
| Age, mean years (±SD) | 57.9±11.0 | 51.2±14.0 | 48.4±11.4 | 60.0±14.7 |
| Female sex, n (%) | 40 (60.6) | 809 (62.1) | 63 (58.9) | 26 (48.1) |
| BCG,* n (%) | 11 (16.7) | 152 (11.7) | 39 (36.4) | 3 (5.6) |
| Prior TB,† n (%) | 12 (18.2) | 15 (1.2) | 4 (3.8) | 3 (5.6) |
| Contact,† n (%) | 13 (19.7) | 52 (4.0) | 16 (15.0) | 1 (1.9) |
| CXR,‡ n (%) | 13 (19.7) | 7 (0.5) | 2 (1.9) | 5 (9.3) |
| CRF,† n (%) | 27 (40.9) | 69 (5.3) | 21 (19.6) | 6 (11.1) |
Data represent patient numbers (%) positive for vaccination or stated risk factor unless otherwise indicated.
CRF was defined as the presence of at least one of the following three clinical risk factors: history of prior TB, close contact and chest x-ray suggestive of LTBI (CXR).
↵* Twenty-one patients with missing BCG data were excluded from BCG analyses (18 in TST−/IGRA− and 1 each in the other 3 groups).
↵† Five patients with missing results for prior TB and close contact (1 in TST−/IGRA+, 4 in TST−/IGRA−) were excluded from these analyses and from the CRF analysis.
‡ CXR was performed in 86.0–96.3% of patients in each group.
BCG, Bacille Calmette-Guérin; CRF, compound risk factor; IGRA, interferon-γ release assay; LTBI, latent tuberculosis infection; TST, tuberculin skin test.