Characteristics of the study population (n=2921)
| Statin users (n=317) | Non-users (n=2604) | ||
|---|---|---|---|
| Variables | Means (SD) or n (%) | Means (SD) or n (%) | p Value |
| Age, years | 64.1 (5.6) | 65.9 (6.8) | <0.001 |
| Female, % | 178 (56.3) | 1495 (57.4) | 0.71 |
| Body mass index, kg/m2 | 26.4 (3.48) | 26.27 (3.4) | 0.45 |
| Femoral bone mineral density, g/cm2 | 0.9 (0.13) | 0.85 (0.13) | 0.11 |
| Plasma total cholesterol/high-density lipoprotein ratio | 6.5 (2.13) | 5.11 (1.5) | <0.001 |
| Arterial hypertension | 111 (35.4) | 707 (27.4) | 0.01 |
| Peripheral artery disease | 30 (10.1) | 230 (9.6) | 0.80 |
| Smoker | 79 (25.2) | 539 (20.8) | 0.07 |
| Diabetes mellitus | 31 (9.8) | 176 (6.8) | 0.05 |
| Higher education | 60 (9.6) | 546 (10.5) | 0.44 |
| Follow-up period (months) | 77.7 (4.3) | 77.78 (4.5) | 0.70 |
| Femur fracture | 0 (0.0) | 2 (0.1) | 0.62 |
| Hip fracture | 10 (3.2) | 130 (5.0) | 0.15 |
| Kellgren and Lawrence score ≥2 of left knee | |||
| Baseline | 25 (8.5) | 279 (11.8) | 0.09 |
| Follow-up | 34 (11.8) | 383 (16.4) | 0.04 |
| Kellgren and Lawrence score ≥2 of right knee | |||
| Baseline | 32 (10.9) | 341 (13.9) | 0.16 |
| Follow-up | 38 (13.1) | 481 (19.7) | 0.01 |
| Kellgren and Lawrence score ≥2 of left hip | |||
| Baseline | 15 (4.7) | 133 (5.2) | 0.74 |
| Follow-up | 20 (6.3) | 198 (7.7) | 0.37 |
| Kellgren and Lawrence score ≥2 of right hip | |||
| Baseline | 16 (5.0) | 171 (6.6) | 0.28 |
| Follow-up | 26 (8.2) | 264 (10.3) | 0.24 |