Table 1

Sample characteristics at baseline by zygosity, showing mean MRI trait scores for whole group and by age strata

Age, yearsMonozygotic twinsDizygotic twinsp Value
Sample size180288
Age, years, mean (range)55.42 (40.89–68.74)52.64 (40.08–68.75)<0.01
Males, n (%)12120.233
Body mass index, kg/m2 (range)24.39 (18.85–42.31)25.01 (17.51–45.14)0.10
Lumbar disc height score, mean (range)All ages4.07 (0–13)3.80 (0–12)0.25
<503.08 (1.59)3.48 (2.24)0.33
50–603.95 (2.44)3.80 (3.36)0.64
>605.2142 (3.15)4.49 (2.71)0.23
Lumbar disc signal score, mean (range)All ages6.21 (0–11)5.65 (0–12)0.03
<504.19 (2.29)4.64 (2.69)0.37
50–606.37 (2.44)5.80 (2.60)0.09
>607.57 (2.20)7.41 (2.15)0.73
Lumbar disc bulge score, mean (range)All ages2.15 (0–8)1.97 (0–10)0.24
<501.83 (1.42)1.87 (1.64)0.89
50–602.12 (1.707)1.84 (1.54)0.20
>602.5 (1.81)2.47 (1.77)0.94
Lumbar anterior osteophyte score, mean (range)All ages1.40 (0–7)0.99 (0–10)<0.01
<501.14 (1.59)0.77 (1.11)0.13
50–601.24 (1.16)0.96 (1.22)0.08
>602.0 (1.82)1.53 (2.06)0.25
Summary lumbar score, mean (range)All ages13.84 (0–38)12.41 (0–40)0.02
<5010.25 (4.93)10.77 (5.78)0.63
50–6013.68 (6.08)12.39 (6.05)0.12
>6017.29 (6.55)15.91 (6.86)0.32
  • Summary lumbar score represente for all four traits over five lumbar disc levels. p Value is significance value comparing monozygotic with dizygotic twins.