Summary of genotype and association results for the two SNPs mapping to the IL-13 gene vicinity for UK/Ireland cases and controls
| SNP | Genotype | Controls (n = 5533) | PsA cases (n = 937) | |||||
|---|---|---|---|---|---|---|---|---|
| Count/Frq | RAF | HWE | Count/Frq | RAF | ptrend | OR (CI) | ||
| rs1800925 | CC | 3715 (67.1) | 690 (73.6) | 1.33 (1.16 to 1.53) | ||||
| CT | 1619 (29.3) | 0.82 | 0.82 | 224 (23.9) | 0.86 | 6.1×10−5 | ||
| TT | 180 (3.3) | 20 (2.1) | ||||||
| rs20541 | GG | 3749 (67.8) | 679 (72.5) | 1.27 (1.10 to 1.45) | ||||
| GA | 1604 (29.0) | 0.82 | 0.82 | 234 (25.0) | 0.86 | 8.0×10−4 | ||
| AA | 175 (3.2) | 18 (1.9) | ||||||
Genotype counts are presented with frequencies in parentheses.
HWE, Hardy–Weinberg equilibrium (reported in controls only); RAF, risk allele frequency.