Comparisons of the CFTR mutation frequencies in patients with both RA and DB and in patients with RA only or DB only
| CFTR mutations | OR | 95% CI | p Value | |
|---|---|---|---|---|
| RA-DB (N=30) vs RA only (N=24) | All mutations | 5.30 | 2.48 to 11.33 | 1.6×10−5 |
| A* | 2.55 | 0.44 to + inf | 0.24 | |
| B | 4.20 | 0.79 to 22.35 | 0.092 | |
| C | 2.89 | 1.01 to 8.25 | 0.047 | |
| RA-DB (N=30) vs DB only (N=8) | All mutations | 0.51 | 0.18 to 1.43 | 0.199 |
| A* | 0.26 | 0.04 to 1.13 | 0.04 | |
| B | 1.54 | 0.29 to 8.12 | 0.614 | |
| C | 1.74 | 0.44 to 6.81 | 0.428 |
↵* Use of exact logistic regression.
See text for classification of CFTR mutations.
RA, rheumatoid arthritis; DB, diffuse bronchiectasis; RA-DB, RA-associated DB.