Results of linear random effects analysis: mean difference in HAQ score over time by parity and association between HAQ score and latency
| Adjustment | Parous vs nulliparous (95% CI) | Change in HAQ score by latency (95% CI) |
|---|---|---|
| Age at symptom onset, symptom duration | −0.19 (−0.32 to −0.06)* | 0.06 (0.02 to 0.10)* |
| As above plus SES, smoking history, RF status, ACPA status, comorbidity and satisfaction of ACR criteria for RA | −0.19 (−0.34 to −0.05)* | 0.05 (0.002 to 0.09)* |
Change in HAQ score by latency is per decade increase in latency.
Comorbidity is number of patient-reported comorbid conditions (by ICD-10 chapter).
Patients with RA met the 1987 ACR criteria for RA at least once during follow-up.
↵* Significant difference/change.
ACPA, anticitrullinated peptide antibodies; HAQ, Health Assessment Questionnaire; RF, rheumatoid factor; SES, socioeconomic status by occupation; smoking history at baseline (ever smoked vs never smoked).