Relative risk (RR) of self-reported physician diagnosed incident gout according to age at natural menopause among women who never used postmenopausal hormones in the Nurses' Health Study
| Age at menopause | Person-years | Number of cases | Age-adjusted RR (95% CI) | Multivariate-adjusted RR* (95% CI) |
|---|---|---|---|---|
| <45 | 17852 | 40 | 1.50 (1.05 to 2.16) | 1.62 (1.12 to 2.33) |
| 45–49 | 80650 | 149 | 1.18 (0.95 to 1.46) | 1.20 (0.97 to 1.49) |
| 50–54 | 140958 | 236 | 1.00 (ref) | 1.00 (ref) |
| ≥55 | 20857 | 37 | 1.10 (0.77 to 1.56) | 1.06 (0.75 to 1.51) |
↵* Adjusted for age, body mass index, use of diuretics, history of hypertension, smoking, alcohol intake, daily average intake of meats, seafood, dairy, coffee, energy-adjusted fructose and vitamin C, and total energy intake.