HLA-class II allelic frequencies significantly associated with African-American patients with systemic sclerosis (SSc) compared with normal African-American controls using logistic regression
| SSc (%) | Controls (%) | Model (D/R/A) | p Value | OR | 95% CI | |
|---|---|---|---|---|---|---|
| DRB1† | ||||||
| *0804 | 10.2 | 3.6 | D | 0.0003 | 3.31 | 1.7 to 6.5 |
| DQA1† | ||||||
| *0501 | 34.2 | 24.1 | A | 0.003 | 3.55 | 1.6 to 8.1 |
| 1.63 | 1.1 to 2.5 | |||||
| DQB1† | ||||||
| *0301 | 33.0 | 21.9 | D | <0.0001 | 2.44 | 1.6 to 3.7 |
↵† SSc cases (n = 178) versus normal controls (n = 263).