Sample size | PADI4_94 allele 2 vs 1 | ||||
---|---|---|---|---|---|
Study | Population | RA cases | Controls | OR (95% CI) | p Value |
Martinez (2005)9 | Spain | 248 | 394 | 1.01 (0.80 to 1.26) | 1.00 |
Harney (2005)8 | UK | 100 | 94 | 1.20 (0.80 to 1.80) | 0.41 |
Plenge (2005): EIRA10 | Sweden | 1498 | 858 | 1.01 (0.89 to 1.14) | 0.93 |
Plenge (2005): NARAC10 | North America | 895 | 748 | 1.24 (1.06 to 1.42) | 0.003 |
Hoppe (2006)13 | German | 102 | 102 | 1.55 (1.05 to 2.30) | 0.04 |
Costenbader (2008)19 | North America | 430 | 426 | 1.07 (0.89 to 1.30) | 0.49 |
WTCCC | UK | 1859 | 10599 | 0.98 (0.91 to 1.05) | 0.58 |
Current cohort | UK | 3732 | 3039 | 1.02 (0.95 to 1.09) | 0.72 |
EIRA, Epidemiological Investigation of Rheumatoid Arthritis; NARAC, North American Rheumatoid Arthritis Consortium; SE, shared epitope; WTCCC, Wellcome Trust Case Control Consortium.