Incidence of hospitalisations due to shingles in population aged ≥18 years exposed to TNF antagonists
| Cases | Person-years | Incidence rate per 100 000 (95% CI) | SIR per 100 000 (95% CI) | SIR (95% CI) | |
|---|---|---|---|---|---|
| BIOBADASER 2.0 | |||||
| All rheumatic diseases exposed to TNF antagonist | 5 | 15389 | 32 (14 to 78) | 29 (9 to 67) | 9 (3 to 20) |
| Rheumatoid arthritis exposed to TNF antagonist | 4 | 9055 | 44 (17 to 118) | 34 (9 to 87) | 10 (3 to 26) |
| CMBD (expected) | 3825 | 114279124 | 3.4 (3.2 to 3.5) | 3.4 (3.2 to 3.5) | |
BIOBADASER, Registro Español de Acontecimientos Adversos de Terapias Biológicas en Enfermedades Reumáticas; CMBD, Conjunto Mínimo Básico de Datos al Alta Hospitalaria (Hospital Discharge Database); SIR, standardised incidence ratio; TNF, tumour necrosis factor.