n | %CD4+FOXP3+ (mean) | 95% CI | |
Non-oligoarticular* | 27 | 6.48 | 5.54 to 7.43 |
Systemic† | 4 | 4.79 | 2.31 to 7.27 |
Polyarticular RF+ | 7 | 7.32 | 5.44 to 9.20 |
Polyarticular RF– | 10 | 6.57 | 5.00 to 8.14 |
Extended oligoarticular | 6 | 6.49 | 4.45 to 8.51 |
Persistent oligoarticular*† | 22 | 8.19 | 7.00 to 9.39 |
Healthy controls | 33 | 6.91 | 6.05 to 7.78 |
*When individual ILAR subtypes were compared there was a significant difference between the systemic and persistent oligoarticular ILAR subtypes (p = 0.031); Games–Howell post hoc test analysis (which accounts for the differing group sizes).
†Regulatory T cells (TReg ) were significantly higher in the persistent oligoarticular group when compared with the non-oligoarticular group (p = 0.044) but not healthy controls (p = 0.720).
ILAR, International League of Associations for Rheumatology; RF, rheumatoid factor.