Response variable | Investigator-defined TSA | Stage V TSA | ||
Total duration of adalimumab exposure | Total duration of adalimumab exposure | |||
1 year (n = 11), (%) | 2 years (n = 8), (%) | 1 year (n = 8), (%) | 2 years (n = 5), (%) | |
ASAS20 | 72.7 | 75.0 | 62.5 | 60.0 |
ASAS40 | 36.4 | 62.5 | 37.5 | 40.0 |
ASAS 5/6 | 54.5 | 37.5 | 37.5 | 20.0 |
ASAS partial remission | 9.1 | 0 | 12.5 | 0 |
BASDAI 50 | 45.5 | 62.5 | 50.0 | 60.0 |
ASAS, ASsessment in Ankylosing Spondylitis International Working Group criteria for improvement; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; TSA, total spinal ankylosis.
*All data are based on observed efficacy analyses.