Table 2 Health Assessment Questionnaire (HAQ) score is positively associated with radiographic progression rate independently of disease activity (Disease Activity Score (DAS) and C-reactive protein (CRP)): generalised mixed linear modelling*

Parameter	Regression coefficient	p Value	95% CI of the regression coefficient
Parameter	Regression coefficient	p Value	Lower bound	Upper bound
Intercept	−0.0142	0.922	−0.3007	0.2723
Sex (F)	−0.3118	<0.001	−0.4307	−0.1928
Age (years)	0.0120	<0.001	0.0080	0.0159
Disease duration (years)	0.0113	0.057	−0.0015	0.0241
CRP (mg/dl)	0.0024	0.085	0.0003	0.0051
Treatment	0.0026	0.934	−0.0997	0.0649
DAS	0.2313	<0.001	0.1969	0.2658
Change in Sharp score (Sharp units/year)	0.0088640	0.001	0.0035	0.0143

*Dependent variable: HAQ