Table 1

HLA-DRB1 genotypic frequencies and seropositivity of autoantibodies among the 288 patients with chronic hepatitis C

DRB1 type	Antibody	No/subtotal	OR G	95% CI p⩽	Antibody	No/subtotal	OR G	95% CI p⩽	Antibody	No/subtotal	OR G	95% CI p⩽
Single allele found in HLA-DR11 type (DRB1*1101), HLA-DR12 type consists of several alleles.
AutoAb¹, seropositive for any one of the autoantibodies tested; AutoAb², seropositive for any one of the autoantibodies tested other than antinuclear antibodies; OR, odds ratio; 95% CI, 95% confidence interval of the OR; G, log likelihood ratio; NS, non-significant.
DR11	ANA(+)	2/67	0.2	0.05 to 0.7	ATG(+)	0/14	0.2	0 to 3.5	AutoAb¹(+)	11/125	0.5	0.2 to 1.0
	ANA(−)	37/221	10.746	0.001	ATG(−)	39/274	4.185	0.0408	AutoAb¹(−)	28/163	4.409	0.0357

DR2	RF(+)	10/52	0.4	0.2 to 0.9	MPO(+)	2/12	0.3	0.1 to 1.2	AutoAb²(+)	16/82	0.4	0.2 to 0.7
	RF(−)	86/236	6.128	0.0133	MPO(−)	101/273	4.02	0.045	AutoAb²(−)	80/206	10.47	0.0012

	ATG(+)	2/14	0.4		AMC(+)	4/24	0.4	0.1 to 1.2
	ATG(−)	94/274		NS	AMC(−)	92/264	3.651	0.056

DR12	AutoAb²(+)	29/82	2.1	1.2 to 3.6	RF(+)	17/52	1.6		AMC(+)	10/24	2.4	1.0 to 5.4
	AutoAb²(−)	43/206	6.298	0.0121	RF(−)	55/236		NS	AMC(−)	62/264	3.507	0.0611

DRB1*0403	ATG(+)	3/14	6.4	1.7 to 24.0	AMC(+)	4/24	5.4	1.6 to 17.6
	ATG(−)	12/274	4.76	0.0291	AMC(−)	11/264	5.323	0.021

DRB1*1401	RF(+)	10/22	2.7	1.1 to 7.0	ATG(+)	0/14	0.43		AMC(+)	0/24	0.24	0.0 to 4.25
	RF(−)	29/236	3.539	0.066	ATG(−)	20/274		NS	AMC(−)	20/264	3.163	0.0573

DRB1*1405	PR3(+)	2/14	6.3	1.4 to 27.8	MPO(+)	3/15	6.4	1.7 to 24.0
	PR3(−)	11/274	4.777	0.0228	MPO(−)	11/273	4.76	0.0291