Clinical characteristics of four liver transplant recipients with rapid and multifocal chondrolysis
| Characteristics | Case 1 | Case 2 | Case 3 | Case 4 |
|---|---|---|---|---|
| *Age at time of transplantation. | ||||
| AZA, azathioprine; CyA, ciclosporin A; P, prednisone; R, right; L, left; GH, glenohumeral joint. | ||||
| Age*/sex | 54/F | 25/M | 21/F | 30/F |
| Liver disease | Primary biliary cirrhosis | Hepatitis B related cirrhosis | Autoimmune cirrhosis | Primary sclerosing cholangitis |
| Immunosuppressive drugs | AZA, CyA, P | AZA, CyA, P | AZA, CyA, P | AZA, CyA, P |
| Time since liver transplant at joint symptom onset (years) | 2 | 6 | 2 | 12 |
| Steroid dose at joint symptom onset (mg/day) | 13 | 8 | 7 | 2 |
| Joints affected and time to complete chondrolysis | R hip/18 mo | L hip/16 mo | RL hips/14 mo | L knee/14 mo |
| L hip/14 mo | R hip/18 mo | RL knees/20 mo | RL ankles | |
| RL knees/20 mo | R GH | RL GH | R hip/12 mo | |