C trachomatis genes identified in the BLAST search using M tuberculosis persistence related genes as query
| Metabolism gene ID/name* | C trachomatis gene ID/name† | Gene function | E value |
|---|---|---|---|
| *UNK, gene of unknown function; †C trachomatis genes indicated in bold were chosen for real time RT-PCR transcript analyses, as indicated in the text. | |||
| Metabolism: | |||
| Rv3114/UNK | Ct844/yfhC | Cytosine deaminase | 6.00E-04 |
| Rv2976c/ung | Ct067/ytgA | N-Uracyl glycosylase | 1.00E-34 |
| Rv3868/UNK | Ct040/ruvB | Holliday Junction DNA helicase | 2.00E-05 |
| Rv2241/aceE | Ct750/tktB | Transketolase | 9.00E-05 |
| Rv1028c/kdpD | Ct205/pfpA | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase | 5.00E-03 |
| Rv2857c/UNK | Ct237/fabG | 3-Oxyacyl (acyl-carrier protein) reductase | 8.00E-37 |
| Rv1238/sugC | Ct202/oppF | Oligopeptide ABC transporter protein | 3.00E-25 |
| Rv2048c/pks12 | Ct770/fabF | β-Ketoacyl-ACP synthase | 2.00E-21 |
| Rv3502c/UNK | Ct237/fabG | 3-Oxyacyl (acyl-carrier protein) reductase | 8.00E-21 |
| Rv0687/UNK | Ct237/fabG | 3-Oxyacyl (acyl-carrier protein) reductase | 9.00E-19 |
| Rv1144/UNK | Ct237/fabG | 3-oxyacyl (acyl-carrier protein) reductase | 8.00E-18 |
| Rv1013/pks16 | Ct776/aas | 2-Acylglycerophosphoethanolamine acyltransferase | 5.00E-14 |
| Rv1185c/fad21 | Ct776/aas | 2-Acylglycerophosphoethanolamine acyltransferase | 9.00E-06 |
| Rv2502c/accD1 | Ct265/accA | Acetyl-CoA carboxylase transferase subunit α | 6.00E-03 |
| Rv099/fad10 | Ct776/aas | 2-Acylglycerophosphoethanolamine acyltransferase | 8.00E-02 |
| Rv2692/trkB | Ct714/gpsA | Glycerol-3-phosphate dehydrogenase | 9.00E-02 |
| Rv1111c/UNK | Ct451/cdsA | Phosphatidate cytidylytransferase (CDP diglyceride) | 3.00E-01 |
| Rv3556c/fadA6 | Ct770/fabF | β-Ketoacyl-ACP synthase | 7.00E-01 |
| Cell envelope related: | |||
| Rv1109c/UNK | Ct414/pmpC | Outer membrane protein C (Chlamydia-specific) | 3.00E-01 |
| Rv3484/cpsA | Ct414/pmpC | pmpC : outer membrane protein C (Chlamydia-specific) | 6.00E-01 |
| Rv2335/cysE | Ct243/firA | UDP-3-O-(3-hydoxymyristoyl)-glucosamine-N-acyltransferase | 1.00E-02 |
| Rv2335/cysE | Ct531/lpxA | UDP-N-acetylglucosamine acyltransferase | 1.00E-02 |
| Rv2981/ddlA | Ct762/murC | MUR-NAc-l-alanine and d-alanine-d-alanine ligase | 2.00E-36 |
| Rv3717/UNK | Ct268/amiA | Probable N-acetylmuramoyl-l-alanine amidase | 1.00E-07 |
| Cellular processes: | |||
| Rv2921c/ftsY | Ct820/ftsY | Signal recognition particle | 6.00E-46 |
| Rv3870/UNK | Ct739/ftsK | Cell division protein (ATPase) | 1.00E-13 |
| Rv3871/UNK | Ct739/ftsK | Cell division protein (ATPase) | 8.00E-02 |
| Rv2912c/UNK | Ct570/gspF | Type II secretion pathway protein (protein F) | 6.80E-01 |
| Rv1821/secA2 | Ct701/secA | Preprotein translocase subunit A protein | 1.00E-62 |
| Transport and binding: | |||
| Rv1469/ctpD | Ct727/zntA | Cation-transporting ATPase | 1.00E-78 |
| Rv3270/ctpC | Ct727/zntA | Cation-transporting ATPase | 2.00E-65 |
| Rv1272c/UNK | Ct264/msbA | ABC transporter protein, MSD-NBD fusion protein | 2.00E-56 |
| Rv3663c/dppD | Ct689/690/201/202 | Oligopeptide ABC transporter protein | 7.00E-46 |
| Rv2936/drrA | Ct653/yhbG | Probable ABC transporter atp binding protein | 2.00E-27 |
| Rv0655/UNK | Ct130/glnQ | Glutamine ABC transporter | 1.00E-23 |
| Rv3758c/proV | Ct130/180 glnQ/tauB | ABC transporter, ATP-binding protein | 6.00E-23 |
| Rv2038c/UNK | Ct202/689 | ABC transporter protein | 2.00E-20 |
| Rv3781/UNK | Ct653/yhbG | Probable ABC transporter ATP-binding | 1.00E-11 |
| Rv3501c/UNK | Ct194/mgtE | Mg2+ transport protein | 4.00E-01 |
| Rv2813/UNK | Ct130/glnQ | Glutamine ABC transporter | 1.00E+00 |
| Translation: | |||
| Rv2845c/proS | Ct393/proS | Prolyl-tRNA synthetase | 4.00E-88 |
| Rv1640c/lysX | Ct781/lysS | Lysyl tRNA synthetase | 9.00E-69 |
| Rv3375/amiD | Ct003/gluA | Glu-tRNA Gln amidotransferase subunit | 1.00E-52 |
| Rv3419c/gcp | Ct197/gcp2 | O-Sialoglycoprotein endopeptidase | 6.00E-49 |
| Rv3560c/fadE30 | Ct437/fusA | Elongation factor G protein | 6.00E-01 |
| Rv3563/fadE32 | Ct437/fusA | Elongation factor G protein | 6.00E-01 |
| Rv3210c/UNK | Ct459/prfB | Peptide chain release factor RF-2 | 8.60E-01 |
| Rv0101/nrp | Ct766/miaA | 2-Acylglycerophosphoethanolamine acyltransferase | 4.00E-04 |
| Regulatory functions: | |||
| Rv2374c/hrcA | Ct394/hrcA | Heat inducible transcription regulator HrcA | 1.00E-14 |
| Rv3246c/mtrA | Ct468/pilR | Two component sensor system regulatory subunit | 3.00E-08 |
| Rv0490/senX3 | Ct467/pilS | Two component sensor histidine kinase (ATOS related) | 2.00E-07 |
| Rv2483c/UNK | Ct743/hctA | Hc1 histone analogue | 2.00E-04 |
| Biosynthesis of cofactors: | |||
| Rv2388c/hemN | Ct052/hemN | Oxygen independent coproporphyrinogen III oxidase | 2.00E-34 |
| Rv1569/bioF | Ct777/bioF | 8-Amino-7-oxononanoate synthase | 2.00E-20 |
| Rv1568/bioA | Ct210/hemL | Glutamate-1-semialdehyde 2,1-aminomutase | 9.00E-16 |
| Rv1405c/UNK | Ct428/ubiE | Probable ubiquiUNK/menaquiUNK methyltransferase | 5.00E-04 |
| Chlamydia other and uncategorised: | |||
| Rv3877/UNK | Ct115/UNK | Hypothetical protein (basic) | 2.00E-01 |
| Rv3910/UNK | Ct624/mviN | MviN virulence factor | 8.00E-09 |
| Rv0670/end | Ct625/end4 | Endonuclease iv | 2.00E-16 |
| Rv3876/UNK | Ct868/UNK | Conserved hypothetical protein | 2.00E-08 |
| Rv3103c/UNK | Ct868/UNK | Conserved hypothetical protein | 9.00E-06 |
| Rv3683/UNK | Ct461/UNK | Conserved hypothetical protein | 2.00E-05 |
| Rv1021/UNK | Ct255/UNK | Conserved hypothetical protein (acidic) | 9.00E-05 |
| Rv3400/UNK | Ct464/UNK | Conserved hypothetical protein | 1.00E-04 |
| Rv0171/UNK | Ct868/UNK | Conserved hypothetical protein | 2.00E-03 |
| Rv3723/UNK | Ct664/UNK | Conserved hypothetical protein | 4.00E-03 |
| Rv3810/pirG | Ct456/UNK | Conserved hypothetical protein | 5.00E-01 |